At the 2023 Chicago Dental Society Midwinter Meeting, Director of Biomaterials, University of Birmingham School of Dentistry, Nate Lawson, DMD, PhD, discusses Infinix from nobio, and the technology behind it.
Read MoreDental restorative materials that contain QASi have sustained antibacterial properties, have mechanical properties comparable to those of presently marketed materials, and have been cleared by the US Food and Drug Administration. Clinical studies have shown that composites incorporating QASi have the potential to markedly reduce the occurrence of caries around restorations. Because caries around restorations is a major problem, restorative materials with sustained antibacterial properties will have an important effect in reducing secondary caries around restorations.
Read MoreA new approach for addressing recurrent caries is the use of antibacterial restorative materials incorporating quaternary ammonium compounds (QACs). QACs are positively charged molecules that are attracted to the negatively charged cell walls of bacteria. A long chain of the QAC can bind to and penetrate the bacterial cell wall and cause leakage of its cytoplasmic contents. Therefore, the mechanism of action of QAC-containing materials is a “contact kill.” QAC molecules have been incorporated into silica filler particles, known as QA silica (QASi) particles. Currently, the only commercially available resin composite containing these QASi particles is Infinix (Nobio Ltd).
Read MoreThe Jan-Feb 2023 edition of Dentistry Today features Dr. Yuval Wind’s clinical article discussing the use of minimally invasive techniques and antimicrobial agents to treat rampant caries.
Read MoreThe use of composites in everyday dentistry is very popular due to their numerous advantages. In combination with adhesive-based technology, it allows one to remove less tooth structure and offer minimally invasive care as well as undetectable restorations that blend into the surrounding tooth structure. Resin composites are certainly popular, but when compared with other materials, their longevity leaves something to be desired. Most experts agree that composite restorations last from 5 to 7 years, often with failure resulting from marginal breakdown and the penetration of bacteria leading to demineralization.
Read MoreDrs Yuval Wind and Gregori Kurtzman describe the synergy between the infinix bonding agent, with its own FDA-cleared antimicrobial claim, and infinix composites, which have been shown in human studies to reduce demineralization of tooth structure, a critical part of the caries process, by up to 68%. Further, the article addresses aspects the filler / chemistry and abbreviated clinical steps.
Read MoreThank you Nathaniel Lawson DMD PhD, for the excellent investigation (University of Alabama) of the properties and performance of the Infinix™ Universal Composite and the valuable comparison to other leading brands in the market. Nobio is extremely proud of the findings!
Read MoreAt this year’s GNYDM, Nobio’s booth traffic benefitted from mention by notable KOLs including Dr. Robert Lowe, Dr. Gordon Christensen, Dr. Travis Nelson and others, as well as an aggressive publicity/support program. The 12,000 attendees made for a productive and busy meeting for Nobio.
Read MoreAmid the noise and haste of the mid-town Manhattan holiday season, a group of leading clinicians and academicians met for an exclusive, invitation-only, session during the Greater New York meeting. Sponsored by Nobio, the event featured a strategic company update by Ronen Raz, Nobio CEO, followed by an impactive technical briefing by Professor John Featherstone, Dean Emeritus of UCSF School of Dentistry.
Read MoreHere is a look at what Lou Shuman, DMD, CAGS, considers the top dental industry impacts for 2022.
Read MoreThank you, Dr. Trudy Lev-Dor, oral medicine specialist and a hospital dentistry consultant for Maccabi Dent, for providing an excellent lecture and hands-on training workshops introducing and demonstrating the new Infinix™ product line and its innovative technology.
Read MoreDental restorative materials that contain QASi have sustained antibacterial properties suggests a recent study published in the Journal of the American Dental Association.
Read MoreNobio’s Infinix™ Flowable Composite and Bulk Fill Flow Composite dental composite restoratives fill the cavities with material designed to match the patient’s natural tooth shade and strength. These FDA- cleared products incorporate Nobio’s patented QASi particle technology that supports restoration integrity and protects against degradation by bacteria over time.
Read MoreThe power of healing and the power of prevention are two concepts that are meaningful to any dental practitioner. Nobio Limited from Israel has introduced a suite of FDA-cleared materials that incorporate antibacterial technology that prevents demineralization at the tooth-restorative interface. Maintaining marginal integrity greatly reduces the chance of secondary decay.
Read MoreOral biofilm is found in the periodontal sulcus, which is a difficult area for patients to maintain with home care. Even for patients without visible oral biofilm, the bacteria within the sulcus and interproximally between the papilla and tooth produce acids as they break down the carbohydrates in the food. Recurrent caries and demineralization around teeth that have had a direct restoration relate to the abundant, intraoral bacteria.
Read MoreRecent years have witnessed exciting developments in dental restorative technologies, especially in the realms of composites and bioactive materials designed to streamline procedures and improve outcomes. Besides bioactive restoratives and cements formulated to prevent demineralization, promote remineralization, and stimulate dentin formation when used as a liner or pulp-capping agent, clinicians can now choose composites and bonding agents featuring caries-fighting antimicrobial properties. And then there’s the debut of single-shade composite systems which simplify restorative care and inventory needs, while also saving valuable chairtime.
Read MoreMichal Dekel-Steinkeller, Ervin I. Weiss, Trudi Lev-Dor Samovici, Itzhak Abramovitz, Journal of Dentistry 123 (2022)
In early February 2022, Gregori Kurtzman, DDS, began to use Nobio Infinix™ for his restorative dentistry. Infinix is an antimicrobial composite and is the first of its kind to fight bacteria continuously while acting as a restorative material. Dr Kurtzman sees Infinix as a great boon for his practice in the Washington Metro Area in Maryland.
Read MoreImagine a future where composites last for a decade or more. Imagine restoring your high caries rate patients with a material that actually kills the bacteria that causes that decay. The best part is that you no longer have to imagine those scenarios. They exist right now.
Read MoreThe composite has integrated into it non-toxic proprietary antimicrobial nanoparticles that once placed creates an anticaries interface that will eliminate secondary caries. Say again? Game changer yes! The future will see it incorporated into varnish, aligners, retainers, ortho cement, implants, root canal sealers, and more. Dr. Lou Shuman, “Top 5 Game Changers of 2021, ”Dental Products Report, Dec 2, 2021.
(Antimicrobial composite)
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